I take 3 of these when I wake in morning.   You need to have them 2 hours after eating anything and 2 hours before eating anything or they just help you digest.

This was from a good Amazon review.

Most of the medical research on the efficacy of systemic oral enzymes aka proteolytic enzymes (PE), such as are contained in this product, has been done outside the US, particularly in Europe. One of the chief, well documented functions of PE is to lower levels of inflammation throughout the body. Inflammation is implicated in virtually every known disease…It has also been demonstrated to be of great help as an adjunct therapy to conventional cancer treatment, or a treatment for cancer in and of itself. Research over the past 30 years on the efficacy of PE has shown that they help prevent metastasis of cancer, which comes about due to the inevitable presence of circulating tumor cells (CTC’s), which are released into the bloodstream during a tumor biopsy, during surgery to remove tumors, and in general via what is called the “shedding” of CTC’s in the general course of cancer’s invasion of the body.
there have been over 30 years of research in Europe with a focus on the influence of PE on the metastasis of cancer, which is defined as the formation of “secondary tumors” due to the spread of CTC’s from the primary tumor site. It is well known among oncologists that it is far more common for secondary tumors to kill a patient than the primary tumor. Tragically, to varying degrees this is due not only to the CTC’s themselves but to the side effects of radiation and chemo, which are so ineffectively used to combat them, because those therapies are well known to be carcinogenic in and of themselves.

Since the 1960s, European scientists have hypothesized that what causes CTC’s to form tumors is the “stickiness” of those CTC’s, which causes them to lodge in a given part of the body and form a malignant tumor. This hypothesis further states that this stickiness results from a deficiency in PE. Stickiness of cancer cells is generally recognized to result from the body’s excessive formation of fibrin aka fribrinogen. There is a close relationship between fibrin deposits and invasive, cancerous tissue growth and metastasis of cancer. One way to find and read some of this research is to search the internet for the term “adhesion molecules.” Fibrin forms on the membrane of tumor cells, which has two dangerous functions. First, it supports adhesion of the tumor cells, that is their “stickiness,” into the formation of a malignant tumor. Second, the fibrin acts as a barrier that defends the CTC’s, and the malignant tumor that they clump together to form, against recognition by the immune  system. Every human being constantly has cancer cells floating around within their body, but a healthy immune system routinely seeks them out and destroys them–as long as the immune system can see/recognize those cells. Thus, by inhibiting excess fibrin formation throughout the body, PE acts to inhibit the spread of CTC’s and the formation of tumors from those CTC’s.

An associated significant effect of fibrin formation is inflammation (see above), which is a well known aspect of the spread of cancer. In that regard, there has been much research indicating a strong increase in cancer risk of patients suffering from chronic inflammatory diseases. A current, comprehensive list of of inflammatory diseases would be at least 100 diseases long, including, for example: asthma, hepatitis, colitis, dermatitis, all forms of arthritis, Alzheimer’s, ankylosing spondylitis, Chrohn’s disease, dermatitis, diverticulitis, atherosclerosis, nephritis, and Parkinson’s disease. It is also well known that certain cancers are caused by infectious agents, such as the association between stomach cancer and the bacteria Helicobacter pylori, and the association between liver cancer and infection with the hepatitis B or C virus. This is because chronic infection is characterized by a state of chronic inflammation.

The way that inflammation plays a role in the spread of cancer is this: Endothelium is a type of epithelium (thin tissue that forms the outer layer of the surface of the body and lines hollow structures in the interior of the body, particularly blood and lymphatic vessels). Edothelium creates an interface between circulating blood or lymph and a given vessel wall and consists of a thin layer of simple squamous cells called endothelial cells. Squamous cells are flat cells which look like the scales of a fish. Most of the cells within the epidermis (the outer layer of the skin), the linings of the hollow organs of the body, and the passages within the digestive and respiratory tracts consist of squamous cells. The endothelium of tissue that has been altered by chronic inflammation has a thick layer of adhesion molecules, and this trait of “stickiness” is strongly associated with sites where metastasis of cancer occurs.

increased survival time is due to a reduction of the spread of cancer. How? Due to reducing the adhesion or “stickiness” of CTC’s.

In addition to its direct link to the formation of malignant tumors, fibrin deposits within joints are frequently mentioned in scientific research in the US and abroad as a prominent feature of arthritis; it strongly contributes to the inflammation that damages joints. In addition, US and European scientists have known for decades that fibrin has consistently been shown to be strongly and independently related to cardiovascular disease

http://n.wobenzymonline.com/wobenzym-research/systemicoralenzymesincancertherapy

Systemic Oral Enzymes in Cancer Therapy

the U.S. Food and Drug Administration has approved investigational new drug status for use of a systemic oral enzyme preparation (i.e., Wobe-Mugos® from Mucos Pharma GmbH) in treatment of Multiple Myeloma. It was found that treatment with Wobe-Mugos® in addition to conventional chemotherapy prolongs remission times in stage II multiple myeloma patients and reduces the concentrations of progression markers.

WOBE-MUGOS is not available in US but Wobenzyme N has the same  ingredients – Chymotrypsin and papain might be the active ingredients.  But Wobenzyme N is half as concentrated – so they think that you can take twice as much of this as the Wobe-MUGOS.

These benefit overall immunity and help reduce the side effects of chemo and radiation.

• Wobenzyme N seems to inhibit Metastasis (spread of cancer).
• Multiple Myeloma (prolongs remission)
• Stomach cancer (5400 patients increased survival rate in more than 505 of patients)
• Colon cancer (patients survived longer)
• Pancreatic cancer (substantial reduction in pain and one to two years longer survival)
• Gynecological cancers all seem to have better outcomes

Another study

Retrolective cohort study of an additive therapy with an oral enzyme preparation in patients with multiple myeloma.

Sakalová A1, Bock PR, Dedík L, Hanisch J, Schiess W, Gazová S, Chabronová I, Holomanova D, Mistrík M, Hrubisko M.

256 patients with MM in 2 groups  half with chemo and half with chemo plus oral enzymes for 6 months.

Control group Stage 1 followup  33 mo, stage 2 follow up  37 mo, Stage 3 follow up 31.5 mo

chemo plus Oral Enzymes stage 1 follow up 61 months, stage 2 follow up 51.5 mo, stage 3 follow up 46.5 months

Significantly higher overall response rates and longer duration of remissions were observed in the group that added oral enzymes.  It decreased the hazard of death for patients at all stages of disease by about 60%!!  Stage 1 & 11 were still alive, but Stage 3 survived 83 months when oral enzymes were added compared to 47 months in the control group.